| LEC # | TOPICS | KEY DATES |
|---|---|---|
| 1 | Physical Structure of the Gene | |
| 2 | The Complementation Test and Gene Function | |
| 3 | Mendelian Genetics | |
| 4 | Probability and Pedigrees | |
| 5 | Chromosomes and Sex Linkage | |
| 6 | Recombination and Genetic Maps | |
| 7 | Three-factor Crosses | |
| 8 | Tetrad Analysis | Problem set #1 due |
| 9 | Phage Genetics | |
| 10 | Gene Structure and DNA Analysis | |
| 11 | Mutations and Suppressors | Problem set #2 due |
| 12 | Bacterial Genetics: Transposition | |
| No lecture: in class exam | Quiz I (Lectures 1-10) | |
| 13 | Bacterial Genetics: Transduction | |
| 14 | Complementation in Bacteria: Plasmids | |
| 15 | Complementation in Bacteria: Recombinant DNA | |
| 16 | Prokaryotic Regulation: Negative Control | |
| 17 | Prokaryotic Regulation: Positive Control | |
| 18 | Prokaryotic Regulation: Regulatory Circuits | Problem set #3 due |
| 19 | Eukaryotic Genes and Genomes I | |
| 20 | Eukaryotic Genes and Genomes II | |
| 21 | Eukaryotic Genes and Genomes III | Problem set #4 due |
| 22 | Eukaryotic Genes and Genomes IV | |
| No lecture: in class exam | Quiz II (Lectures 11-18) | |
| 23 | Transgenes and Gene Targeting in Mice I | |
| 24 | Transgenes and Gene Targeting in Mice II | |
| 25 | Population Genetics: Hardy-Weinberg | |
| 26 | Population Genetics: Mutation and Selection | |
| 27 | Population Genetics: Inbreeding | |
| 28 | Human Polymorphisms | |
| 29 | Statistical Evaluation of Linkage I | Problem set #5 due |
| 30 | Statistical Evaluation of Linkage II | |
| 31 | Complex Traits | Problem set #6 due |
| 32 | Chromosome Anomalies I | |
| No lecture: in class exam | Quiz III (Lectures 19-30) | |
| 33 | Chromosome Anomalies II | |
| 34 | Genetics of Cancer I | |
| 35 | Genetics of Cancer II | |
| Final Exam |