Calendar

Lec # TOPICS LECTURERS KEY DATES
Part I. Principles of Tissue Engineering: Scaffolds and Cells
1

Course Overview/Clinical Problems for Tissue Engineering Solution

Introduction to Tissue Engineering in China

Scaffolds: Introduction

Scaffolds: Collagen-GAG Analogs of Extracellular Matrix

Prof. Spector, MIT / Prof. Cui, Tsinghua University

Prof. Cui, Tsinghua University

Prof. Spector, MIT

Prof. Yannas, MIT

2

Cells: Liver Cells

Scaffolds: Recent Advances in Tissue Engineering

Yingxin Xu, M. D., and Qingling Feng, Ph. D., Tsinghua University

Prof. Langer, MIT

3

Scaffolds: Free-Form Manufacturing

Scaffolds: Self-Assembled Proteins

Review

Prof. Yan, Tsinghua University

Dr. S. Zhang, MIT

Prof. Spector, MIT

4

Cells: Sources

Cells: Differentiated versus Stem Cells

Dr. C. Vacanti, MIT

Prof. Spector, MIT

Part II. Principles of Tissue Engineering: Cells and Regulators
5

Scaffolds: Biomimetics Design

Cells: Effects of Culture Conditions

Review

Prof. Cui, Tsinghua University

Dr. L. Freed, MIT

Prof. Spector, MIT

Homework 1 due
6 Quiz 1 Homework 2 due
7

Regulators: Response to Mechanical Loading

Regulators: Roles of Environmental Factors

Prof. Grodzinsky, MIT

Dr. Vunjak-Novakovic, MIT

8

Cells: Embryonic and Other Stem Cell for Tissue Engineering

Gene Therapy

Regulators: Gene Transfer Wedded to Tissue Engineering

Prof. Guo, Tsinghua University

Dr. Zhijie Chang, Tsinghua University

Prof. Evans, Harvard Medical School

Part III. Practice of Tissue Engineering: Clinical Applications
9

Applications: Skin and Peripheral Nerve

Nerve Repair

Discussion: Clinical Applications

Prof. Yannas, MIT

Xiufang Zhang, Nanming Zhao, Yandao Gong, Tsinghua University

Prof. Spector, MIT

10

Blood Vessels

Heart Valves

Discussion: Comparative Analysis of Tissue Engineering Strategies

Prof. Schoen, Harvard Medical School

Dr. W. B. Li, Tsinghua University

Prof. Spector, MIT

11

Urinary Tissues/Organs

Clinical Applications and Underlying Principles

Prof. Atala, MIT

Prof. Y. Cao, Tsinghua University

Homework 3 due
12

Bone Regeneration

Cartilage Repair

Discussion: Review

Dr. Yu Xing, Tsinghua University, and Prof. Yan Wang, M. D., General Hospital of Peoples' Liberation Army

Prof. Spector, MIT

Prof. Spector, MIT

Report due
13

Federal Regulatory Issues for Tissue Engineering Products in the U.S., China, and Other Countries

Brain Repair

Review

Prof. Spector, MIT

Prof. Cui, Tsinghua University

Prof. Spector, MIT / Prof. Cui, Tsinghua University

Homework 4 due
14 Quiz 2