Lecture Notes

Instructors

MK: Prof. Mehran Kardar
LM: Prof. Leonid Mirny

SES # TOPICS INSTRUCTORS
1 Introduction; Master equation MK
2 Elements of population genetics LM
3 Evolving populations (forward Kolmogorov) MK
4 Population genetics (fitness, selection, ...) LM
5 Fixation (backward Kolmogorov) MK
6 Introduction to sequence alignment LM
7 Algorithms for sequence alignment LM
8 Significance of aligments (extreme value distributions) MK
9 Ionic interactions MK
10 Polymer theory 1, entropy elasticity, collapse MK
11 Polymer theory 2, collapse, Random energy model MK
12 Protein folding 1: elements of structure and forces LM
13 Protein folding 2: evolved (designed) foldable proteins LM
14 Protein folding 3: kinetics LM
15 Protein folding 4: kinetics LM
16 DNA (melting) MK
17 RNA (secondary structure) MK
18 Protein-DNA interactions 1: specific and non-specific binding LM
19 Protein-DNA interactions 2: sequence-dependence & kinetics LM
20 Microtubules MK
21 Molecular motors & cell motility MK
22 Introduction to networks MK
23 Dynamics on networks 1 MK
24 Dynamics on networks 2 LM
25 Packing of DNA inside cells LM
26 Cooperativity: hemoglobin and transcription factors LM